Physiological Roles for mafr-1 in Reproduction and Lipid Homeostasis
Maf1 is a conserved repressor of RNA polymerase (Pol) III transcription; however, its physiological role in the context of a multicellular organism is not well understood. Here, we show that C. elegans MAFR-1 is functionally orthologous to human Maf1, represses the expression of both RNA Pol III and...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-12-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714010018 |