Physiological Roles for mafr-1 in Reproduction and Lipid Homeostasis

Maf1 is a conserved repressor of RNA polymerase (Pol) III transcription; however, its physiological role in the context of a multicellular organism is not well understood. Here, we show that C. elegans MAFR-1 is functionally orthologous to human Maf1, represses the expression of both RNA Pol III and...

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Bibliographic Details
Main Authors: Akshat Khanna, Deborah L. Johnson, Sean P. Curran
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714010018