Association of genetic ancestry with HER2, GRB7 AND estrogen receptor expression among Colombian women with breast cancer

Association of genetic ancestry with HER2, GRB7 AND estrogen receptor expression among Colombian women with breast cancer

BackgroundOur previous study reported higher mRNA levels of the human epidermal growth factor receptor 2 (HER2)-amplicon genes ERBB2 and GRB7 in estrogen receptor (ER)-positive breast cancer patients with relatively high Indigenous American (IA) ancestry from Colombia. Even though the protein expres...

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Bibliographic Details
Main Authors: Laura Rey-Vargas, Lina María Bejarano-Rivera, Juan Carlos Mejia-Henao, Luz F. Sua, Jhon Faustino Bastidas-Andrade, Carlos Andrés Ossa, Luz Dary Gutiérrez-Castañeda, Laura Fejerman, María Carolina Sanabria-Salas, Silvia J. Serrano-Gómez
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
breast neoplasms
American native continental ancestry
receptor ErbB-2
GRB7 adaptor protein
estrogen receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.989761/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.989761/full

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