Self-assembled FGF21 nanoparticles alleviate drug-induced acute liver injury

Self-assembled FGF21 nanoparticles alleviate drug-induced acute liver injury

Acetaminophen (N-acetyl-p-aminophenol, APAP) is a common antipyretic agent and analgesic. An overdose of APAP can result in acute liver injury (ALI). Oxidative stress and inflammation are central to liver injury. N-acetylcysteine (NAC), a precursor of glutathione, is used commonly in clinical settin...

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Bibliographic Details
Main Authors: Zhiwei Huang, Hengcai Wang, Changju Chun, Xinze Li, Shihao Xu, Yingzheng Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
fibroblast growth factor 21
nanoparticles
liver-targeted therapy
oxidative stress
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1084799/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1084799/full

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