Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells

Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells

Estrogen (E2) and Progesterone (Pg), via their specific receptors (ERalpha and PR), are major determinants in the development and progression of endometrial carcinomas, However, their precise mechanism of action and the role of other transcription factors involved are not entirely clear. Using Ishik...

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Bibliographic Details
Main Authors: Alejandro La Greca, Nicolás Bellora, François Le Dily, Rodrigo Jara, Ana Silvina Nacht, Javier Quilez Oliete, José Luis Villanueva, Enrique Vidal, Gabriela Merino, Cristóbal Fresno, Inti Tarifa Reischle, Griselda Vallejo, Guillermo Vicent, Elmer Fernández, Miguel Beato, Patricia Saragüeta
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-01-01
Series:eLife
Subjects:
progesterone receptor
PAX2
estrogen receptor
gene regulation
ChIPseq
Online Access:https://elifesciences.org/articles/66034

Internet

https://elifesciences.org/articles/66034

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