DNA Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive Therapy

DNA Methylation of the t-PA Gene Differs Between Various Immune Cell Subtypes Isolated From Depressed Patients Receiving Electroconvulsive Therapy

BackgroundMajor depressive disorder (MDD) represents a tremendous health threat to the world’s population. Electroconvulsive therapy (ECT) is the most effective treatment option for refractory MDD patients. Ample evidence suggests brain-derived neurotrophic factor (BDNF) to play a crucial role in EC...

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Bibliographic Details
Main Authors: Nicole Moschny, Kirsten Jahn, Malek Bajbouj, Hannah Benedictine Maier, Matthias Ballmaier, Abdul Qayyum Khan, Christoph Pollak, Stefan Bleich, Helge Frieling, Alexandra Neyazi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Psychiatry
Subjects:
brain-derived neurotrophic factor
tissue-type plasminogen activator
depression
immunology
DNA methylation
electroconvulsive therapy remission
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2020.00571/full

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https://www.frontiersin.org/article/10.3389/fpsyt.2020.00571/full

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