Protocol for generating liver metastasis microtissues to decipher cellular interactions between metastatic intestinal cancer and liver tissue

Summary: Cell competition is a quality control mechanism that promotes elimination of suboptimal cells relative to fitter neighbors. Cancer cells exploit these mechanisms for expansion, but the underlying molecular pathways remain elusive. Here, we present a protocol for generating matrix-free micro...

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Podrobná bibliografie
Hlavní autoři: Maria Lamprou, Ana Krotenberg Garcia, Saskia Jacoba Elisabeth Suijkerbuijk
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2025-03-01
Edice:STAR Protocols
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2666166724007408