Establishment and validation of a cholesterol metabolism-related prognostic signature for hepatocellular carcinoma

Establishment and validation of a cholesterol metabolism-related prognostic signature for hepatocellular carcinoma

Hepatocellular carcinoma (HCC) represents the most important type of liver cancer, the 5-year survival rate for advanced HCC is 2%. The heterogeneity of HCC makes previous models fail to achieve satisfactory results. The role of Cholesterol-based metabolic reprogramming in cancer has attracted more...

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Bibliographic Details
Main Authors: Linsong Tang, Rongli Wei, Ronggao Chen, Guanghan Fan, Junbin Zhou, Zhetuo Qi, Kai Wang, Qiang Wei, Xuyong Wei, Xiao Xu
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Hepatocellular carcinoma
Cholesterol metabolism
Prognostic signature
Therapeutic response
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022003105

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http://www.sciencedirect.com/science/article/pii/S2001037022003105

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