Single-cell RNA sequencing reveals Immune Education promotes T cell survival in mice subjected to the cecal ligation and puncture sepsis model

Single-cell RNA sequencing reveals Immune Education promotes T cell survival in mice subjected to the cecal ligation and puncture sepsis model

BackgroundIndividual T cell responses vary significantly based on the microenvironment present at the time of immune response and on prior induced T cell memory. While the cecal ligation and puncture (CLP) model is the most commonly used murine sepsis model, the contribution of diverse T cell respon...

Full description

Bibliographic Details
Main Authors: Steven D. Ham, Mabel N. Abraham, Clifford S. Deutschman, Matthew D. Taylor
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
cecal ligation and puncture
mouse sepsis model
sepsis
T cell
CD4
CD8
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1366955/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1366955/full

Similar Items