Bayesian phylogeny analysis of vertebrate serpins illustrates evolutionary conservation of the intron and indels based six groups classification system from lampreys for ∼500 MY
The serpin superfamily is characterized by proteins that fold into a conserved tertiary structure and exploits a sophisticated and irreversible suicide-mechanism of inhibition. Vertebrate serpins are classified into six groups (V1–V6), based on three independent biological features—genomic organizat...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2015-06-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/1026.pdf |