Characterizing Protease Specificity: How Many Substrates Do We Need?

Characterizing Protease Specificity: How Many Substrates Do We Need?

Calculation of cleavage entropies allows to quantify, map and compare protease substrate specificity by an information entropy based approach. The metric intrinsically depends on the number of experimentally determined substrates (data points). Thus a statistical analysis of its numerical stability...

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Bibliographic Details
Main Authors: Michael Schauperl, Julian E Fuchs, Birgit J Waldner, Roland G Huber, Christian Kramer, Klaus R Liedl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4641643?pdf=render

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http://europepmc.org/articles/PMC4641643?pdf=render

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