In vivo FRET imaging revealed a regulatory role of RanGTP in kinetochore-microtubule attachments via Aurora B kinase.

Under the fluctuating circumstances provided by the innate dynamics of microtubules and opposing tensions resulted from microtubule-associated motors, it is vital to ensure stable kinetochore-microtubule attachments for accurate segregation. However, a comprehensive understanding of how this regulat...

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Bibliographic Details
Main Authors: Yoke-Peng Lee, Chi-Hang Wong, Kheng-Sze Chan, Soak-Kuan Lai, Cheng-Gee Koh, Hoi-Yeung Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3461030?pdf=render