Breast Cancer Molecular Subtypes Differentially Express Gluconeogenic Rate-Limiting Enzymes—Obesity as a Crucial Player

Breast Cancer Molecular Subtypes Differentially Express Gluconeogenic Rate-Limiting Enzymes—Obesity as a Crucial Player

Breast cancer is a heterogeneous entity, where different molecular subtypes (MS) exhibit distinct prognostic and therapeutic responses. A series of 62 breast cancer samples stratified by MS was obtained from the tumor biobank of IPO-Porto. The expression of glycolysis and gluconeogenesis-regulating...

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Bibliographic Details
Main Authors: Carla Luís, Fernando Schmitt, Rute Fernandes, Nuno Coimbra, Joana Rigor, Paula Dias, Dina Leitão, Rúben Fernandes, Raquel Soares
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
breast cancer
molecular subtype
obesity
cancer cell metabolism
Warburg effect
glycolysis
Online Access:https://www.mdpi.com/2072-6694/15/20/4936

Internet

https://www.mdpi.com/2072-6694/15/20/4936

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