CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation

CD31 signaling promotes the detachment at the uropod of extravasating neutrophils allowing their migration to sites of inflammation

Effective neutrophil migration to sites of inflammation is crucial for host immunity. A coordinated cascade of steps allows intravascular leukocytes to counteract the shear stress, transmigrate through the endothelial layer, and move toward the extravascular, static environment. Those events are tig...

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Bibliographic Details
Main Authors: Francesco Andreata, Marc Clément, Robert A Benson, Juliette Hadchouel, Emanuele Procopio, Guillaume Even, Julie Vorbe, Samira Benadda, Véronique Ollivier, Benoit Ho-Tin-Noe, Marie Le Borgne, Pasquale Maffia, Antonino Nicoletti, Giuseppina Caligiuri
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-08-01
Series:eLife
Subjects:
CD31
neutrophils
transmigration
iigrins
ITIM
Online Access:https://elifesciences.org/articles/84752

Internet

https://elifesciences.org/articles/84752

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