Random Forest model reveals the interaction between N6-methyladenosine modifications and RNA-binding proteins

Summary: RNA-binding proteins (RBPs) have critical roles in N6-methyladenosine (m6A) modification process. We designed a Random Forest (RF) model to systematically analyze the interaction among RBPs and m6A modifications by integrating the binding signals from hundreds of RBPs. Accurate prediction o...

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Bibliographic Details
Main Authors: Wei Hong, Yanding Zhao, Yi-Lan Weng, Chao Cheng
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003279