A Multidisciplinary Approach Establishes a Link between Transglutaminase 2 and the Kv10.1 Voltage-Dependent K<sup>+</sup> Channel in Breast Cancer

A Multidisciplinary Approach Establishes a Link between Transglutaminase 2 and the Kv10.1 Voltage-Dependent K<sup>+</sup> Channel in Breast Cancer

Since the multifunctionality of transglutaminase 2 (TG2) includes extra- and intracellular functions, we investigated the effects of intracellular administration of TG2 inhibitors in three breast cancer cell lines, MDA-MB-231, MDA-MB-436 and MDA-MB-468, which are representative of different triple-n...

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Bibliographic Details
Main Authors: Rita Canella, Federica Brugnoli, Mariana Gallo, Jeffrey W. Keillor, Anna Terrazzan, Elena Ferrari, Silvia Grassilli, Eric W. J. Gates, Stefano Volinia, Valeria Bertagnolo, Nicoletta Bianchi, Carlo M. Bergamini
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
breast cancer
MDA-MB-231 cells
transglutaminase 2
transglutaminase inhibitors
AA9
Kv10.1
Online Access:https://www.mdpi.com/2072-6694/15/1/178

Internet

https://www.mdpi.com/2072-6694/15/1/178

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