Different doses of nalmefene combined with hydromorphone hydrochloride for postoperative analgesia after colorectal surgery: a randomized controlled study

Abstract Background Hydromorphone hydrochloride has a satisfactory postoperative analgesic effect for patients with colorectal cancer but is accompanied by a relatively high incidence of adverse events. Low-doses of naloxone combined with opioids for patient-controlled analgesia can reduce the incid...

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Bibliographic Details
Main Authors: Ye Wang, Lin Zhao, Meng Wu, Qi An, Qianqian Guo, Chunling Fan, Zhenggang Guo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Surgery
Subjects:
Online Access:https://doi.org/10.1186/s12893-023-02293-z