Selective protein aggregation confines and inhibits endotoxins in wounds: Linking host defense to amyloid formation

Selective protein aggregation confines and inhibits endotoxins in wounds: Linking host defense to amyloid formation

Summary: Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and...

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Bibliographic Details
Main Authors: Jitka Petrlova, Erik Hartman, Ganna Petruk, Jeremy Chun Hwee Lim, Sunil Shankar Adav, Sven Kjellström, Manoj Puthia, Artur Schmidtchen
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Immunology
Bacteriology
cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422302028X

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http://www.sciencedirect.com/science/article/pii/S258900422302028X

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