Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species.

Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species.

The cellular and molecular mechanisms underpinning the unusually high virulence of highly pathogenic avian influenza H5N1 viruses in mammalian species remains unknown. Here, we investigated if the cell tropism of H5N1 virus is a determinant of enhanced virulence in mammalian species. We engineered H...

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Bibliographic Details
Main Authors: Smanla Tundup, Matheswaran Kandasamy, Jasmine T Perez, Nacho Mena, John Steel, Tamas Nagy, Randy A Albrecht, Balaji Manicassamy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5362246?pdf=render

Internet

http://europepmc.org/articles/PMC5362246?pdf=render

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