Calcium Signaling Alterations Caused by Epigenetic Mechanisms in Pancreatic Cancer: From Early Markers to Prognostic Impact

Calcium Signaling Alterations Caused by Epigenetic Mechanisms in Pancreatic Cancer: From Early Markers to Prognostic Impact

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with high mortality rates. PDAC initiation and progression are promoted by genetic and epigenetic dysregulation. Here, we aimed to characterize the PDAC DNA methylome in search of novel altered pathways associated with tumor developmen...

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Bibliographic Details
Main Authors: Cleandra Gregório, Sheila Coelho Soares-Lima, Bárbara Alemar, Mariana Recamonde-Mendoza, Diego Camuzi, Paulo Thiago de Souza-Santos, Raquel Rivero, Simone Machado, Alessandro Osvaldt, Patricia Ashton-Prolla, Luis Felipe Ribeiro Pinto
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
pancreatic ductal adenocarcinoma
calcium signaling pathway
DNA methylation
early methylation alterations
prognostic biomarkers
Online Access:https://www.mdpi.com/2072-6694/12/7/1735

Internet

https://www.mdpi.com/2072-6694/12/7/1735

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