Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review

Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review

Senescence suppresses tumor growth, while also developing a tumorigenic state in the nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The dual function of cellular senescence stresses the need for identifying multi-targeted agents directed towards the promotion of...

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Bibliographic Details
Main Authors: Sajad Fakhri, Seyed Zachariah Moradi, Angela Ash-Rafzadeh, Anupam Bishayee
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Pharmacological Research
Subjects:
Plant secondary metabolites
Phytochemicals
Cancer
Senescence
Autocrine
Paracrine
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661821005454

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http://www.sciencedirect.com/science/article/pii/S1043661821005454

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