Molecular mechanics and dynamics simulation of CD-47/SIRPα blockade study: A computational study on overcoming immunotherapeutic resistance in pancreatic ductal adenocarcinoma

Molecular mechanics and dynamics simulation of CD-47/SIRPα blockade study: A computational study on overcoming immunotherapeutic resistance in pancreatic ductal adenocarcinoma

The sting of pancreatic ductal adenocarcinoma remains an irksome burden to the human populace. The focus of recent research has switched from finding the perfect medicinal medication to blocking immunological checkpoint proteins such as the signal regulating protein alpha-cluster of differentiation...

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Bibliographic Details
Main Authors: Oluwatosin A. Saibu, Temitope M. Ajayi, Damilola A. Omoboyowa, Oladapo O. Oladipo, Sodiq O. Hammed, Tope T. Odunitan, Adenrele T. Oluwafemi, Aderonke J. Adejuyigbe, Gideon O. Aloba, Toheeb A. Balogun, Abdullahi O.Alausa, Damilola S. Bodun
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Arabian Journal of Chemistry
Subjects:
PDAC
CD47
SIRPα
ADME
In silico
Immunotherapeutic
Online Access:http://www.sciencedirect.com/science/article/pii/S187853522300727X

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http://www.sciencedirect.com/science/article/pii/S187853522300727X

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