Natural killer cells modified with a Gpc3 aptamer enhance adoptive immunotherapy for hepatocellular carcinoma

Abstract Introduction Natural killer cells can attack cancer cells without prior sensitization, but their clinical benefit is limited owing to their poor selectivity that is caused by the lack of specific receptors to target tumor cells. In this study, we aimed to endow NK cells with the ability to...

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Bibliographic Details
Main Authors: Youshi Zheng, Zisen Lai, Bing Wang, Zuwu Wei, Yongyi Zeng, Qiuyu Zhuang, Xiaolong Liu, Kecan Lin
Format: Article
Language:English
Published: Springer 2023-09-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00780-6