Natural killer cells modified with a Gpc3 aptamer enhance adoptive immunotherapy for hepatocellular carcinoma
Abstract Introduction Natural killer cells can attack cancer cells without prior sensitization, but their clinical benefit is limited owing to their poor selectivity that is caused by the lack of specific receptors to target tumor cells. In this study, we aimed to endow NK cells with the ability to...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Springer
2023-09-01
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Series: | Discover Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s12672-023-00780-6 |