Antimalarial evaluation of alkyl-linked bis-thiadiazine derivatives in murine model infected with two Plasmodium strains

Antimalarial evaluation of alkyl-linked bis-thiadiazine derivatives in murine model infected with two Plasmodium strains

Background and Purpose: Plasmodium falciparum and P. vivax are responsible for most malaria cases in humans in the African Region and the Americas; these parasites have developed resistance to classic antimalarial drugs. On the other hand, previous investigations of the alkyl-linked bis tetrahydro-...

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Bibliographic Details
Main Authors: Katherine Stefania Loachamin Gualotuña, Lilian M. Spencer, Hortensia Maria Rodriguez Cabrera, Renata Abigail Montero Calderón, Beatriz Pernía, Julieta Coro, Margarita Suarez, Francisco Javier Tingo Jacome, Zully J. Rodriguez Parra, Jose Manuel Lozano, Jesús Cortés Vecino
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2023-11-01
Series:ADMET and DMPK
Subjects:
Plasmodium berghei
Plasmodium yoelii
Bis-THTT
drugs
parasitemia
humoral response
Online Access:https://pub.iapchem.org/ojs/index.php/admet/article/view/2105

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https://pub.iapchem.org/ojs/index.php/admet/article/view/2105

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