Blocking Adenosine/A2AR Pathway for Cancer Therapy

Blocking Adenosine/A2AR Pathway for Cancer Therapy

Adenosine is a metabolite produced abundantly in the tumor microenvironment, dampening immune response in inflamed tissues via adenosine A2A receptor (A2AR) which is widely expressed on immune cells, inhibiting anti-tumor immune response accordingly. Therefore, blocking adenosine signaling pathway i...

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Bibliographic Details
Main Authors: Jia LIU, Yuequan SHI, Xiaoyan LIU, Dongming ZHANG, Yu BAI, Yan XU, Mengzhao WANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2022-07-01
Series:Chinese Journal of Lung Cancer
Subjects:
tumor microenvironment
adenosine
adenosine receptor
a2ar antagonist
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2022.102.24

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2022.102.24

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