Interpreting a Bayesian phase II futility clinical trial

Abstract Background A resurgence of research into phase II trial design in the mid-2000s led to the use of futility designs in a wide variety of disease areas. Phase II futility studies differ from efficacy studies in that their null hypothesis is that treatment, relative to control, does not meet o...

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Bibliographic Details
Main Authors: Jonathan Beall, Christy Cassarly, Renee Martin
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-022-06877-7