Interpreting a Bayesian phase II futility clinical trial
Abstract Background A resurgence of research into phase II trial design in the mid-2000s led to the use of futility designs in a wide variety of disease areas. Phase II futility studies differ from efficacy studies in that their null hypothesis is that treatment, relative to control, does not meet o...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | Trials |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13063-022-06877-7 |