Host factors that promote retrotransposon integration are similar in distantly related eukaryotes.
Retroviruses and Long Terminal Repeat (LTR)-retrotransposons have distinct patterns of integration sites. The oncogenic potential of retrovirus-based vectors used in gene therapy is dependent on the selection of integration sites associated with promoters. The LTR-retrotransposon Tf1 of Schizosaccha...
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artikkeli |
| Kieli: | English |
| Julkaistu: |
Public Library of Science (PLoS)
2017-12-01
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| Sarja: | PLoS Genetics |
| Linkit: | http://europepmc.org/articles/PMC5741268?pdf=render |