Univariate/multivariate genome-wide association scans using data from families and unrelated samples.

As genome-wide association studies (GWAS) are becoming more popular, two approaches, among others, could be considered in order to improve statistical power for identifying genes contributing subtle to moderate effects to human diseases. The first approach is to increase sample size, which could be...

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Bibliographic Details
Main Authors: Lei Zhang, Yu-Fang Pei, Jian Li, Christopher J Papasian, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2715864?pdf=render