β2-Adrenoceptors in the Medial Prefrontal Cortex Excitatory Neurons Regulate Anxiety-like Behavior in Mice

β2-Adrenoceptors in the Medial Prefrontal Cortex Excitatory Neurons Regulate Anxiety-like Behavior in Mice

The medial prefrontal cortex (mPFC) and β-adrenoceptors (βARs) have been implicated in modulating anxiety-like behavior. However, the specific contributions of the β2-AR subtype in mPFC in anxiety are still unclear. To address this issue, we used optogenetic and microRNA-based (miRNA) silencing to d...

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Bibliographic Details
Main Authors: Zhuogui Lei, Yukyan Lam, Cheukhin Li, Zhongqi Fu, Aruna S. Ramkrishnan, Shu Liu, Ying Li
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
norepinephrine
β2-adrenoceptors
optogenetics
neuronal manipulation
microRNA-based silencing
medial prefrontal cortex
Online Access:https://www.mdpi.com/1422-0067/23/10/5578

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https://www.mdpi.com/1422-0067/23/10/5578

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