Case Report: Prolonged clinical benefit with sequential trastuzumab-containing treatments in a patient with advanced extramammary Paget disease of the groin

Case Report: Prolonged clinical benefit with sequential trastuzumab-containing treatments in a patient with advanced extramammary Paget disease of the groin

Extramammary Paget disease (EMPD) is a rare form of cutaneous, intraepithelial adenocarcinoma, which typically presents itself as an erythematous plaque originating from apocrine-gland rich regions, such as the vulva, the perianal region, the scrotum, the penis, or the axilla. EMPD patients typicall...

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Bibliographic Details
Main Authors: Emma Zattarin, Federico Nichetti, Francesca Ligorio, Laura Mazzeo, Riccardo Lobefaro, Giovanni Fucà, Giorgia Peverelli, Andrea Vingiani, Giulia V. Bianchi, Giuseppe Capri, Filippo de Braud, Claudio Vernieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
extramammary Paget disease (EMPD)
HER2 overexpression
trastuzumab
prolonged benefit
antiandrogen therapy
rare cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.925551/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.925551/full

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