Identifying potential drug targets for varicose veins through integration of GWAS and eQTL summary data

Identifying potential drug targets for varicose veins through integration of GWAS and eQTL summary data

BackgroundVaricose veins (VV) are a common chronic venous disease that is influenced by multiple factors. It affects the quality of life of patients and imposes a huge economic burden on the healthcare system. This study aimed to use integrated analysis methods, including Mendelian randomization ana...

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Bibliographic Details
Main Authors: Yu Cui, Mengting Hu, He Zhou, Jiarui Guo, Qijia Wang, Zaihua Xu, Liyun Chen, Wancong Zhang, Shijie Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-05-01
Series:Frontiers in Genetics
Subjects:
varicose veins
drug targets
Mendelian randomization analysis
colocalization analysis
genome-wide association studies
expression quantitative trait locus
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1385293/full

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https://www.frontiersin.org/articles/10.3389/fgene.2024.1385293/full

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