Peptide Variant Detection by a Living Yeast Biosensor via an Epitope-Selective Protease

We previously demonstrated that we could hijack the fungal pheromone signaling pathway to provide a living yeast biosensor where peptide biomarkers were recognized by G-protein-coupled receptors and engineered to transcribe a readout. Here, we demonstrated that the protease could be reintroduced to...

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Bibliographic Details
Main Authors: Tea Crnković, Benjamin J. Bokor, Mead E. Lockwood, Virginia W. Cornish
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2023-01-01
Series:BioDesign Research
Online Access:https://spj.science.org/doi/10.34133/bdr.0003