Anesthetics rapidly promote synaptogenesis during a critical period of brain development.

Experience-driven activity plays an essential role in the development of brain circuitry during critical periods of early postnatal life, a process that depends upon a dynamic balance between excitatory and inhibitory signals. Since general anesthetics are powerful pharmacological modulators of neur...

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Bibliographic Details
Main Authors: Mathias De Roo, Paul Klauser, Adrian Briner, Irina Nikonenko, Pablo Mendez, Alexandre Dayer, Jozsef Z Kiss, Dominique Muller, Laszlo Vutskits
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2738943?pdf=render