High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale

High-throughput determination of protein affinities using unmodified peptide libraries in nanomolar scale

Summary: Protein-protein interactions (PPIs) are of fundamental importance for our understanding of physiology and pathology. PPIs involving short, linear motifs play a major role in immunological recognition, signaling, and regulation and provide attractive starting points for pharmaceutical interv...

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Bibliographic Details
Main Authors: Clemens Schulte, Vladimir Khayenko, Noah Frieder Nordblom, Franziska Tippel, Violetta Peck, Amit Jean Gupta, Hans Michael Maric
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
Subjects:
Biochemistry Methods
Neuroscience
Biophysical Methods
Biochemistry
Biophysics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220310956

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http://www.sciencedirect.com/science/article/pii/S2589004220310956

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