Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos

Novel variants in TUBB8 gene cause multiple phenotypic abnormalities in human oocytes and early embryos

Abstract Background The genotype-phenotype relationships between TUBB8 variants and female infertility are difficult to clearly define due to the complex inheritance patterns and the highly heterogeneous phenotypes. This study aims to identify novel TUBB8 variants and relevant phenotypes in more inf...

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Bibliographic Details
Main Authors: Tingwenyi Hu, Chong Li, Sen Qiao, Weiwei Liu, Wei Han, Wei Li, Rong Shi, Xia Xue, Juanzi Shi, Guoning Huang, Tingting Lin
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Ovarian Research
Subjects:
Primary female infertility
Oocyte maturation arrest
TUBB8 gene
Genetic counselling
Online Access:https://doi.org/10.1186/s13048-023-01274-3

Internet

https://doi.org/10.1186/s13048-023-01274-3

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