Urolithin A’s Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats

Urolithin A’s Antioxidative, Anti-Inflammatory, and Antiapoptotic Activities Mitigate Doxorubicin-Induced Liver Injury in Wistar Rats

Human colon microbiota produce a metabolite called urolithin A (URO A) from ellagic acid and linked compounds, and this metabolite has been demonstrated to have antioxidant, anti-inflammatory, and antiapoptotic activities. The current work examines the various mechanisms through which URO A protects...

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Bibliographic Details
Main Authors: Shahid Karim, Batoul Madani, Abdulhadi S. Burzangi, Mohammed Alsieni, Mohammed A. Bazuhair, Maha Jamal, Hussam Daghistani, Mohammed O. Barasheed, Huda Alkreathy, Mohammad Ahmed Khan, Lateef M. Khan
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
chemotherapy
drug-induced liver injury
urolithin A
apoptosis
anti-inflammatory
oxidative stress
Online Access:https://www.mdpi.com/2227-9059/11/4/1125

Internet

https://www.mdpi.com/2227-9059/11/4/1125

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