Dipyridamole potentiated the trypanocidal effect of nifurtimox and improved the cardiac function in NMRI mice with acute chagasic myocarditis

BACKGROUND As chronic Chagas disease does not have a definitive treatment, the development of alternative therapeutic protocols is a priority. Dipyridamole (DPY) is an alternative to counteract the pathophysiological phenomena involved in Chagas cardiomyopathy. OBJECTIVE To evaluate the therapeut...

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Hlavní autoři: Sonia Santeliz, Peter Caicedo, Elidiosmar Giraldo, Carmen Alvarez, María-Daniela Yustiz, Claudina Rodríguez-Bonfante, Romina Bonfante-Rodríguez, Rafael Bonfante-Cabarcas
Médium: Článek
Jazyk:English
Vydáno: Fundação Oswaldo Cruz (FIOCRUZ)
Edice:Memorias do Instituto Oswaldo Cruz
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On-line přístup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000900596&lng=en&tlng=en