Distinct populations of antigen-specific tissue-resident CD8+ T cells in human cervix mucosa

Distinct populations of antigen-specific tissue-resident CD8+ T cells in human cervix mucosa

The ectocervix is part of the lower female reproductive tract (FRT), which is susceptible to sexually transmitted infections (STIs). Comprehensive knowledge of the phenotypes and T cell receptor (TCR) repertoire of tissue-resident memory T cells (TRMs) in the human FRT is lacking. We took single-cel...

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Bibliographic Details
Main Authors: Tao Peng, Khamsone Phasouk, Emily Bossard, Alexis Klock, Lei Jin, Kerry J. Laing, Christine Johnston, Noel A. Williams, Julie L. Czartoski, Dana Varon, Annalyssa N. Long, Jason H. Bielas, Thomas M. Snyder, Harlan Robins, David M. Koelle, M. Juliana McElrath, Anna Wald, Lawrence Corey, Jia Zhu
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-08-01
Series:JCI Insight
Subjects:
Immunology
Virology
Online Access:https://doi.org/10.1172/jci.insight.149950

Internet

https://doi.org/10.1172/jci.insight.149950

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