Quorum sensing in CD4+ T cell homeostasis: a hypothesis and a model.

Quorum sensing in CD4+ T cell homeostasis: a hypothesis and a model.

Homeostasis of lymphocyte numbers is believed to be due to competition between cellular populations for a common niche of restricted size, defined by the combination of interactions and trophic factors required for cell survival. Here we propose a new mechanism: homeostasis of lymphocyte numbers cou...

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Bibliographic Details
Main Authors: Afonso R.M. Almeida, Ines F. Amado, Joseph eReynolds, Julien eBerges, Grant eLythe, Carmen eMolina-Paris, Antonio A eFreitas
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Immunology
Subjects:
Autoimmunity
Homeostasis
Quorum Sensing
CD4+ T cells
regulatory T cells
IL-2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00125/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00125/full

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