An anesthesia protocol for robust and repeatable measurement of behavioral visceromotor responses to colorectal distension in mice

IntroductionVisceral motor responses (VMR) to graded colorectal distension (CRD) have been extensively implemented to assess the level of visceral pain in awake rodents, which are inevitably confounded by movement artifacts and cannot be conveniently implemented to assess invasive neuromodulation pr...

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Bibliographic Details
Main Authors: Shaopeng Zhang, Longtu Chen, Bin Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pain Research
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpain.2023.1202590/full