HTLV Tax: a fascinating multifunctional co-regulator of viral and cellular pathways

HTLV Tax: a fascinating multifunctional co-regulator of viral and cellular pathways

Human T cell lymphotropic virus type 1 (HTLV-1) has been identified as the causative agent of adult T cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The virus infects between 15 and 20 million people worldwide of which approximately 2 to 5% develop ATL....

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Bibliographic Details
Main Authors: Robert eCurrer, Rachel eVan Duyne, Elizabeth eJaworski, Irene eGuendel, Gavin eSampey, Ravi eDas, Aarthi eNarayanan, Fatah eKashanchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Microbiology
Subjects:
HTLV-1
NF-κB
tax
oncogenesis
post-translational modification
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00406/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00406/full

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