SARS-CoV-2 evolution in a patient with secondary B-cell immunodeficiency: A clinical case

SARS-CoV-2 evolution in a patient with secondary B-cell immunodeficiency: A clinical case

The article highlights the course of long-term SARS-CoV-2 infection in a patient with a secondary immunodeficiency developed with B-cell-depleting therapy of the underlying disease. Analysis of the intrapatient virus evolution revealed an inpatient S:G75A mutation that alters the 72GTNGTKR78 motif o...

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Bibliographic Details
Main Authors: Olgo A. Mukhina, Daria S. Fomina, Vasiliy V. Parshin, Vladimir A. Gushchin, Inna V. Dolzhikova, Alexey M. Shchetinin, Dmitriy M. Chudakov, Evgeniia Alekseeva, Dmitriy Korostin, Georgii A. Bazykin, Galya Klink, Denis Yu. Logunov, Maryana A. Lysenko
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
immunodeficiency
b-cell depletion
rituximab
coronavirus evolution
covid-19
sars-cov-2
human immunoglobulin
convalescent plasma
normal human intravenous immunoglobulin
Online Access:http://dx.doi.org/10.1080/21645515.2022.2101334

Internet

http://dx.doi.org/10.1080/21645515.2022.2101334

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