Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model
Abstract We have developed a candidate vaccine to protect against multiple strains of Streptococcus pyogenes infections. The candidate vaccine contains two synthetic peptides derived from S. pyogenes proteins: the M-protein epitope, p*17 and the IL-8 degrading S. pyogenes Cell-Envelope Proteinase (S...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-02-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-023-00604-2 |