Development and Optimisation of Tumour Treating Fields (TTFields) Delivery within 3D Primary Glioma Stem Cell-like Models of Spatial Heterogeneity

Development and Optimisation of Tumour Treating Fields (TTFields) Delivery within 3D Primary Glioma Stem Cell-like Models of Spatial Heterogeneity

Glioblastoma is an aggressive, incurable brain cancer with poor five-year survival rates of around 13% despite multimodal treatment with surgery, DNA-damaging chemoradiotherapy and the recent addition of Tumour Treating Fields (TTFields). As such, there is an urgent need to improve our current under...

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Bibliographic Details
Main Authors: Callum G. Jones, Aurelie Vanderlinden, Ola Rominiyi, Spencer J. Collis
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
Tumour Treating Fields
TTFields
glioblastoma
glioma stem-like cells
3D models
DNA damage response inhibitors
Online Access:https://www.mdpi.com/2072-6694/16/5/863

Internet

https://www.mdpi.com/2072-6694/16/5/863

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