The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast

Protein-DNA complexes can impede DNA replication and cause replication fork collapse. Whilst it is known that homologous recombination is deployed in such instances to restart replication, it is unclear how a stalled fork transitions into a collapsed fork at which recombination proteins can load. Pr...

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Bibliographic Details
Main Authors: Sanjeeta Tamang, Anastasiya Kishkevich, Carl A Morrow, Fekret Osman, Manisha Jalan, Matthew C Whitby
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/47277