Structural variation of alpha-synuclein with temperature by a coarse-grained approach with knowledge-based interactions

Despite enormous efforts, our understanding the structure and dynamics of α-synuclein (ASN), a disordered protein (that plays a key role in neurodegenerative disease) is far from complete. In order to better understand sequence-structure-property relationships in α-SYNUCLEIN we have developed a coar...

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Bibliographic Details
Main Authors: Peter Mirau, B. L. Farmer, R. B. Pandey
Format: Article
Language:English
Published: AIP Publishing LLC 2015-09-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.4927544