Structural variation of alpha-synuclein with temperature by a coarse-grained approach with knowledge-based interactions
Despite enormous efforts, our understanding the structure and dynamics of α-synuclein (ASN), a disordered protein (that plays a key role in neurodegenerative disease) is far from complete. In order to better understand sequence-structure-property relationships in α-SYNUCLEIN we have developed a coar...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2015-09-01
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Series: | AIP Advances |
Online Access: | http://dx.doi.org/10.1063/1.4927544 |