A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans

A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen Candida albicans

ABSTRACTCandida albicans, one of the most prevalent human fungal pathogens, causes diverse diseases extending from superficial infections to deadly systemic mycoses. Currently, only three major classes of antifungal drugs are available to treat systemic infections: azoles, polyenes, and echinocandin...

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Bibliographic Details
Main Authors: Sara Fallah, Dustin Duncan, Kyle D. Reichl, Michael J. Smith, Wenyu Wang, John A. Porco, Lauren E. Brown, Luke Whitesell, Nicole Robbins, Leah E. Cowen
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
metal chelator
fungal pathogen
Candida
Aspergillus
iron
chemical library
Online Access:https://journals.asm.org/doi/10.1128/spectrum.04095-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.04095-23

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