Complement Activation via the Lectin and Alternative Pathway in Patients With Severe COVID-19

Complement plays an important role in the direct defense to pathogens, but can also activate immune cells and the release of pro-inflammatory cytokines. However, in critically ill patients with COVID-19 the immune system is inadequately activated leading to severe acute respiratory syndrome (SARS) a...

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Bibliographic Details
Main Authors: Janina Niederreiter, Christine Eck, Tajana Ries, Arndt Hartmann, Bruno Märkl, Maike Büttner-Herold, Kerstin Amann, Christoph Daniel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.835156/full