Exploring differential exon usage via short- and long-read RNA sequencing strategies

Exploring differential exon usage via short- and long-read RNA sequencing strategies

Alternative splicing produces various mRNAs, and thereby various protein products, from one gene, impacting a wide range of cellular activities. However, accurate reconstruction and quantification of full-length transcripts using short-reads is limited, due to their length. Long-reads sequencing tec...

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Bibliographic Details
Main Authors: Dena Leshkowitz, Merav Kedmi, Yael Fried, David Pilzer, Hadas Keren-Shaul, Elena Ainbinder, Bareket Dassa
Format: Article
Language:English
Published: The Royal Society 2022-09-01
Series:Open Biology
Subjects:
alternative splicing
differential exon usage
long-reads
short-reads
embryonic stem cell
RNA-Seq
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220206

Internet

https://royalsocietypublishing.org/doi/10.1098/rsob.220206

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