Isoflavone and its metabolite equol inhibit the development of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumours in ovariectomised rats

Isoflavone and its metabolite equol inhibit the development of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary tumours in ovariectomised rats

Studies have yet to determine whether or not equol can explain the chemopreventive effect of soy. In the present study, a single oral dose of 5 mg 7,12-dimethylbenz(a)anthracene (DMBA) was administered to 120 rats. After ovariectomy, these rats were divided into eight different treatment groups: con...

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Bibliographic Details
Main Authors: Defu Ma, Yumei Zhang, Yong Xue, Peiyu Wang, Titi Yang, Xianglong Shao
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Functional Foods
Subjects:
Isoflavones
Mammary tumours
Equol
Oestrogen receptor
DMBA
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464613003216

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http://www.sciencedirect.com/science/article/pii/S1756464613003216

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