Molecular subtyping of esophageal squamous cell carcinoma by large-scale transcriptional profiling: Characterization, therapeutic targets, and prognostic value

Molecular subtyping of esophageal squamous cell carcinoma by large-scale transcriptional profiling: Characterization, therapeutic targets, and prognostic value

The tumor heterogeneity of the transcriptional profiles is independent of genetic variation. Several studies have successfully identified esophageal squamous cell carcinoma (ESCC) subtypes based on the somatic mutation profile and copy number variations on the genome. However, transcriptome-based cl...

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Bibliographic Details
Main Authors: Danke Wang, Jiacheng Dai, Chen Suo, Shangzi Wang, Yuting Zhang, Xingdong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
ESCC
gene expression profile
subtype
integrate
GSEA
WGCNA
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1033214/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1033214/full

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